Anti-Cholera Toxin B Antibody, Mouse Monoclonal (VACY-0922-CY135)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VACY-0922-CY135 |
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Anti-Cholera Toxin B Antibody, Mouse Monoclonal, Monoclonal Antibody, specific for Cholera Toxin
Datasheet
Specifications
Target
Cholera Toxin
Type
Monoclonal Antibody
Applications
EIA
Formulation
PBS pH7.4, 0.1% sodium azide
Storage
Store at -20 °C
Concentration
1 mg/ml
Information
Introduction
Cholera toxin is a protein complex secreted by the bacterium Vibrio cholerae. The cholera toxin is an oligomeric complex made up of six protein subunits: a single copy of the A subunit (part A, enzymatic), and five copies of the B subunit (part B, receptor binding), denoted as AB5. B subunits bind and internalize A subunits, which are processed to A1. The A1 form catalyses ADP ribosylation from NAD to the regulatory component of adenylate cyclase, thereby activating it. Increased adenylate cyclase activity increases cyclic AMP (cAMP) synthesis causing massive fluid and electrolyte efflux, resulting in diarrhoea.
Alternative Names
Cholera Toxin
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
