Japanese Encephalitis Virus (JEV) is one of the pathogens causing encephalitis. In most cases, the infection caused by the virus does not manifest or manifests mild symptoms, and the virus occasionally causes inflammation in the brain. The virus spreads through mosquitoes, and wild birds and pigs are also hosts for the virus. JEV belongs to the family of Flaviviridae. The viral genome is a single-stranded, positive-sense RNA coated in the capsid. The envelope of the virus is its protective antigen and has the function of assisting the virus to enter the host cell. The viral genome encodes several non-structural proteins, NS1, NS2a, NS2b, NS3, N4a, NS4b, and NS5.
Alternative Names
Japanese encephalitis virus; JEV; Flavivirus; Flaviviridae