Anti-CCR6 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0138-WJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CCR6 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CCR6

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
1235

UniProt ID
P51684

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0138-WJ	CBWJC-0084	Mouse	Human	IgG2a	CD196
DMAb-0139-WJ	CBWJC-0993	Mouse	Human	IgG2b
DMAb-0140-WJ	CBWJC-0994	Mouse	Human	IgG2b, κ	CCR6-transfected cells
DMAb-2702-FY	CBFYC-0222	Mouse	Human	IgG1, k
DMAb-2703-FY	CBFYC-0283	Rat	Mouse	IgG2a	RBL-1 rat basophilic leukemia cell line transfected with mouse CCR6, Met1-Met367
DMAb-2704-FY	CBFYC-0349	Rat	Mouse	IgG2a, k
DMAb-2705-FY	CBFYC-1081	Armenian Hamster	Mouse	IgG	N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
DMAb-2706-FY	CBFYC-1082	Rat	Mouse	IgG2	Recombinant protein corresponding to mouse CCR6
DMAb-2707-FY	CBFYC-1083	Mouse	Human	IgG2	Human CCR6 transfected 293 cells
DMAb-2708-FY	CBFYC-1084	Rat	Mouse	IgG2
DMAb-0171-CQ	CBXC-2908	Mouse		IgG1	Recombinant human CCR6 (1-46aa) purified from E. coli
DMAb-0172-CQ	CBXC-2584	Mouse		IgG2b	Human CCR6 transfected NS0 mouse myeloma cells
DMAb-0173-CQ	CBXC-2876	Mouse		IgG2b	Human CCR6
DMAb-0174-CQ	CBXC-2535	Rat	Mouse	IgG2a	Mouse CCR6
DMAb-0175-CQ	CBXC-0976	Rat		IgG2a	RBL-1 rat basophilic leukemia cell line transfected with mouse CCR6, Met1-Met367, Accession # O54689
DMAb-0176-CQ	CBXC-1236	Mouse		IgG2b	NS0 mouse myeloma cell line transfected with human CCR6, Met1-Met374, Accession # P51684
DMAb-0177-CQ	CBXC-0733	Human		IgG1
DMAb-0178-CQ	CBXC-0160	Mouse		IgG2b
DMAb-0179-CQ	CBXC-1857	Mouse		IgG2a

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CCR6 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0138-WJ)

Specifications

Target

Customer Reviews and Q&As

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