The anti-CD19 chimeric antigen receptor (CAR) Jurkat cell line is a stable cell line derived from anti-CD19 CAR lentivirus transduction. This transduced CAR lentiviral vector was constructed to express scFv of an anti-CD19 antibody linked to the CD28 and CD3ζ signaling domains. And this recombinant cell product can be used to target human CD19 and treat Chronic lymphocytic leukemia (CLL).
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