Anti-FER DNA-encoded mAb (DMAb), pVAX1 (DMAb-0904-CQ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-FER DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
FER

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
2241

UniProt ID
P16591

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0904-CQ	CBXF-1045	Rabbit		IgG
DMAb-0905-CQ	CBXF-0500	Mouse		IgG1
DMAb-0906-CQ	CBXF-0498	Mouse		IgG1
DMAb-0907-CQ	CBXF-2059	Mouse		IgG1
DMAb-0908-CQ	CBXF-2533	Mouse		IgG1	Ni-NTA purified truncated recombinant FER-His expressed in E. coli strain BL21 (DE3)
DMAb-0909-CQ	CBXF-2323	Mouse		IgG1
DMAb-0910-CQ	CBXF-2505	Mouse		IgG1
DMAb-0911-CQ	5D2C4	Mouse		IgG1	Human FER expressed in E. coli
DMAb-0912-CQ	CBXF-3470	Mouse		IgG1, κ
DMAb-0913-CQ	CBXF-0497	Mouse		IgG1
DMAb-0914-CQ	CBXF-3451	Mouse		IgG2a, κ
DMAb-0915-CQ	CBXF-0499	Mouse		IgG1
DMAb-0916-CQ	CBXF-2600	Mouse		IgG1	E. coli-derived recombinant human Fer, Asn93-Ala302
DMAb-0917-CQ	CBXF-0496	Mouse		IgG1	Recombinant human FER
DMAb-0918-CQ	CBXF-2947	Mouse		IgG1	Synthetic peptide corresponding to aa 797-811 of Fer Tyrosine Kinase
DMAb-0919-CQ	CBXF-2948	Mouse		IgG	Partial sequence of recombinant full-length protein to human Fer (fps/fes related) Tyrosine Kinase
DMAb-0920-CQ	CBXF-1581	Mouse		IgG1	Purified recombinant fragment of human FER expressed in E. coli

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-FER DNA-encoded mAb (DMAb), pVAX1 (DMAb-0904-CQ)

Specifications

Target

Customer Reviews and Q&As

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