Anti-GSK3A DNA-encoded mAb (DMAb), pVAX1 (DMAb-1427-LY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-GSK3A DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
GSK3A

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
2931

UniProt ID
P49840

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1427-LY	10C400A	Mouse	Human	IgG2b	Glycogen Synthase Kinase 3 Alpha
DMAb-1428-LY	13A190	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Alpha
DMAb-1429-LY	288901	Mouse	Human	IgG2b	Glycogen Synthase Kinase 3 Alpha
DMAb-1430-LY	5K147	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1431-LY	5K148	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1435-LY	SBGSK3a1	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1436-LY	SBGSK3a2	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1437-LY	SBGSK3a4	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1438-LY	SBGSK3-alpha-2	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1439-LY	SBGSK3-alpha-4	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1443-LY	10C1	Mouse		IgG1	Glycogen Synthase Kinase 3 Alpha
DMAb-1444-LY	13B355	Mouse	Human	IgG	Glycogen Synthase Kinase 3 Alpha
DMAb-1445-LY	13B356	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Alpha
DMAb-1446-LY	13B357	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Alpha
DMAb-1447-LY	34Q36	Mouse	Human	IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1448-LY	3i16	Mouse	Human	IgG2b	Glycogen Synthase Kinase 3 Alpha
DMAb-1449-LY	4H328	Rabbit	Rat	IgG	Glycogen Synthase Kinase 3 Alpha
DMAb-1450-LY	5J105	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1451-LY	5K149	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1452-LY	6G12C2	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Alpha
DMAb-1453-LY	6G2F1	Mouse	Human	IgG	Glycogen Synthase Kinase 3 Alpha
DMAb-1454-LY	D80D1	Rabbit		IgG	Glycogen Synthase Kinase 3 Alpha
DMAb-1455-LY	D80E6	Rabbit		IgG	Glycogen Synthase Kinase 3 Alpha
DMAb-1457-LY	IgG1	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Alpha
DMAb-1252-LY	L5	Rabbit		IgG	Glycogen Synthase Kinase 3 Alpha
DMAb-1459-LY	MS-1G7			IgG	Glycogen Synthase Kinase 3 Alpha
DMAb-1460-LY	SBGSK3-alpha-1	Mouse		IgG2a	Glycogen Synthase Kinase 3 Alpha
DMAb-1461-LY	W15183A	Rat		IgG2a, κ	Glycogen Synthase Kinase 3 Alpha
DMAb-0882-FY	9D5G1	Mouse	Human	IgG1	Ni-NTA purified truncated recombinant GSK3 alpha expressed in E. Coli strain BL21

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-GSK3A DNA-encoded mAb (DMAb), pVAX1 (DMAb-1427-LY)

Specifications

Target

Customer Reviews and Q&As

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