Anti-HPGDS DNA-encoded mAb (DMAb), pVAX1 (DMAb-0387-LY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-HPGDS DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
HPGDS

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0387-LY	G172-1138	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0388-LY	GST01	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0389-LY	P1A12	Mouse		IgG2b, κ	Hematopoietic Prostaglandin D Synthase
DMAb-0390-LY	vpg66	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0406-LY	11C1E136	Rabbit	Chemical	IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0407-LY	11C1E16	Mouse	Bacterial	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0409-LY	15TF2‐1D10	Mouse	Human	IgG1, κ	Hematopoietic Prostaglandin D Synthase
DMAb-0410-LY	16-21	Mouse		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0411-LY	172	Mouse		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0412-LY	17B6	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0413-LY	1B3	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0414-LY	1E1K22E1	Mouse	Chemical	IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0415-LY	2021	HuCAL		Fab	Hematopoietic Prostaglandin D Synthase
DMAb-0416-LY	2031	HuCAL		Fab	Hematopoietic Prostaglandin D Synthase
DMAb-421-YC	3D4	Mouse		IgG2b	Hematopoietic Prostaglandin D Synthase
DMAb-459-YC	3G10	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0420-LY	5C12	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0421-LY	6D42E1	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0422-LY	6E5	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-3441CQ	6G9	Rat	S.japonicum	IgG2a	Hematopoietic Prostaglandin D Synthase
DMAb-0424-LY	8C1-G4	Mouse		IgG2b	Hematopoietic Prostaglandin D Synthase
DMAb-0425-LY	BDI340	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0427-LY	GF1	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0428-LY	GST.B6	Mouse		IgG2a	Hematopoietic Prostaglandin D Synthase
DMAb-0429-LY	KAB29	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0431-LY	L70B11	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0167-CN	Mix	Mouse		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0434-LY	PIP	Hamster		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0435-LY	Q16	Mouse		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0436-LY	Q9	Mouse		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0437-LY	S-tag-02	Mouse		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0438-LY	S-tag-05	Mouse		IgG2b	Hematopoietic Prostaglandin D Synthase
DMAb-0374-LY	21CT54.13.1/21CT54.13.7	Mouse	S.japonicum	IgG1, κ	Hematopoietic Prostaglandin D Synthase
DMAb-0376-LY	26H1	Mouse	All Species	IgG2a	Hematopoietic Prostaglandin D Synthase
DMAb-1215-LY	2A10	Mouse		IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0378-LY	2F10B9	Mouse		IgG	Hematopoietic Prostaglandin D Synthase
DMAb-0379-LY	2H3-D10	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0380-LY	3937	HuCAL		Fab	Hematopoietic Prostaglandin D Synthase
DMAb-0381-LY	3H2162	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-1048-LY	4C10	Mouse		IgG2b	Hematopoietic Prostaglandin D Synthase
DMAb-0383-LY	8A169	Mouse	Chemical	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0384-LY	9AT106	Mouse	S.japonicum	IgG1	Hematopoietic Prostaglandin D Synthase
DMAb-0385-LY	E1-T-177	Mouse	Chemical	IgG	Hematopoietic Prostaglandin D Synthase

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-HPGDS DNA-encoded mAb (DMAb), pVAX1 (DMAb-0387-LY)

Specifications

Customer Reviews and Q&As

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