Anti-KRT14 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0870-WJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-KRT14 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
KRT14

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
3861

UniProt ID
P02533

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0875-WJ	LL002	Mouse		IgG3	A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14
DMAb-0881-WJ	D19-N	Rabbit	Human	IgG	Peptide corresponding to the C-Terminus of human cytokeratin 14
DMAb-1461-CQ	KRT14/284	Mouse		IgG2b, κ	Recombinant Full length human KRT14 protein
DMAb-1462-CQ	KRT14/532	Mouse		IgG3	Recombinant Full length human KRT14 protein
DMAb-0875-WJ	LL002	Mouse		IgG3	A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14
DMAb-0881-WJ	D19-N	Rabbit	Human	IgG	Peptide derived from C-terminal region of human cytokeratin 14
DMAb-1467-CQ	SPK-14	Mouse		IgG2b	Synthetic peptide corresponding to the carboxy-terminal sequence of human cytokeratin 14 (KVVSTHEQVLRTKN) coupled to keyhole limpet hemocyanin
DMAb-1470-CQ	RCK107	Mouse		IgG	A cytoskeletal preparation of TR146 epithelial cells

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-KRT14 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0870-WJ)

Specifications

Target

Customer Reviews and Q&As

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