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Anti-LYZ T cell receptor (72.1), pCDTCR1 (TCR-YC0637)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

T cell hybridoma 72.10, specific for the epitope responded equally well to the epitope and to wild type peptide HEL(11-27), which differs at position 12 (Gly or Glu in the P9 pocket) of the epitope.

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Details

  • Target
  • LYZ
  • Target Species
  • Chicken
  • Epitope
  • AMKRHGLDNYREYSLGN
  • Format
  • Non-Modified TCR
  • Allele
  • H2-IAg7
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • 72.1
  • Host Species
  • Mouse

Target

  • Introduction
  • This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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