Close

Anti-MAGEA3 (EVDPIGHLY) TCR, pMSGV1 (TCR-L062)

The vector of anti-MAGEA3 T cell receptor (TCR) is constructed for the engineering of T cell to target Human MAGEA3. The T cells are genetically modified through transduction with a retroviral vector expressing MAGEA3-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.

Datasheet   Add to Cart

Details

  • Target
  • MAGE-A3
  • Target Species
  • Human
  • Epitope
  • EVDPIGHLY
  • Format
  • Non-modified TCR
  • Allele
  • HLA-A1
  • Targeting Diseases
  • Melanoma
  • Vector Name
  • pMSGV1
  • Vector Length
  • 6700-8070bp
  • Vector Type
  • retroviral vector
  • Host Species
  • Human

Target

  • Official Symbol
  • MAGEA3
  • Introduction
  • This gene is a member of the MAGEA gene family. The members of this family encode proteins with
    50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show
    considerable variability, suggesting that the existence of this gene family enables the same function
    to be expressed under different transcriptional controls. The MAGEA genes are clustered at
    chromosomal location Xq28. They have been implicated in some hereditary disorders, such as
    dyskeratosis congenita.
    Alternative Names MAGEA3; Cancer/Testis

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products

All services and products are only for lab research use, not for any clinical diagnosis or treatment.

Online Inquiry
Products

CONTACT US

USA: 45-1 Ramsey Road, Shirley, NY 11967, USA
UK:167-169 Great Portland Street, 5th Floor, London, W1W 5PE
Germany: Heidenkampsweg 58, 20097 Hamburg, Germany
Call us at:
USA: 1-631-381-2994
UK: 44-207-097-1828
Fax: 1-631-207-8356
Email:

Online Inquiry

For any technical issues or products/services related questions, please leave your information below. Our team will contact you soon.

  • Verification code
    Click image to refresh the verification code.

Key Updates

Receive our latest news and insights.