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The genetically modified anti-PLAC1 TCR-NK cell is designed to target to the specific epitope-HLA complex. The TCR-NK is expected to show antigen-specific cytotoxicity against PLAC1 antigen via the introduced TCR were successfully produced.
| Sub CAT. | HLA | TCR Clone | Epitope | |
| XS-0623-ZP181-SUB1 | HLA-A*0201 | TCRCD8-mPl#11 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB2 | HLA-A*0201 | TCRCD8-mPl#12 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB3 | HLA-A*0201 | TCRCD8-mPl#14 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB4 | HLA-A*0201 | TCRCD8-mPl#17 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB5 | HLA-A*0201 | TCRCD8-mPl#19 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB6 | HLA-A*0201 | TCRCD8-mPl#2 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB7 | HLA-A*0201 | TCRCD8-mPl#20 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB8 | HLA-A*0201 | TCRCD8-mPl#22 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB9 | HLA-A*0201 | TCRCD8-mPl#25 | PMTVLCSIDWFMVTVHPFM | |
| XS-0623-ZP181-SUB10 | HLA-A*0201 | TCRCD8-mPl#8 | aa 28-36, 30-41, best 31-39 | |
| XS-0623-ZP181-SUB11 | HLA-A*0201 | TCRCD8-mPl#9 | PMTVLCSIDWFMVTVHPFM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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