Other Cancer/Viral Infection Specific CAR Construction Service

Are you currently facing challenges in developing effective immunotherapies for difficult-to-treat cancers or persistent viral infections? Our other cancer or viral infection-specific CAR construction service helps you accelerate therapeutic development and achieve highly specific, potent cellular therapies through advanced CAR design and engineering techniques.

Introduction

Besides the main categories of cancer, such as Leukemia, Lymphoma, Carcinoma, Sarcoma, Blastoma, and Germ cell tumors, Creative Biolabs also provides world-class CAR products targeting other cancers, including glioma, tumor vasculature, and viral infections. Our many years of experience and the most advanced techniques enable us to offer you the first-class products according to your specific requirements. Tumor regression mechanisms involve targeting both tumor antigen and tumor vasculature, which helps the tumor grow. Our skilled scientists and technicians have successfully constructed CARs targeting tumor vasculature antigens.

Fig.1 Schematic of lymphodepletion before CAR T infusion on tumor cells and the immune microenvironment.¹

Other Cancer or Viral Infection Specific CAR Construction Service at Creative Biolabs

Creative Biolabs' other cancer or viral infection-specific CAR construction service delivers precisely engineered CAR constructs tailored to your unique therapeutic targets. We provide comprehensive solutions for developing novel CARs against a wide range of "other" cancers, including various gliomas and tumor vasculature antigens, as well as persistent viral infections. Our service is designed to overcome the inherent challenges of these diseases, such as antigen heterogeneity, immunosuppressive microenvironments, and viral latency, by integrating advanced CAR designs that enhance specificity, persistence, and anti-tumor/anti-viral efficacy.

Creative Biolabs has successfully constructed different types of bispecific chimeric antigen receptors (called Tan CAR) modified T cells approaches, which make genetically engineered T cells recognize and target both cancer antigens and latent-virus antigens (such as from attack cytomegalovirus (CMV), EBV, or adenovirus). In addition to the multiple cancer antigens, elite scientists from Creative Biolabs have successfully placed bispecific CAR targeting cancer antigen grafted with latent-virus antigen in T cells to recognize and attack CMV or EBV, or adenovirus, which makes genetically engineered T cells work better to react to the virus as well as to cancer cells.

What We Can Offer

Service Process

Key Advantages

• Expertise in Diverse Targets: Our extensive experience spans beyond conventional CAR targets, encompassing complex solid tumors like various gliomas and tumor vasculature, as well as persistent viral infections.
• Integrated Workflow & Support: From initial target identification and validation to gene synthesis, vector construction, cell transduction, and final deliverables, our seamless, one-stop service ensures efficient project progression.
• Cutting-Edge Technology Integration: We continuously integrate the latest advancements to provide you with innovative solutions that push the boundaries of cellular immunotherapy.

FAQs

Why Choose Us?

Creative Biolabs' other cancer or viral infection-specific CAR construction service offers distinct advantages that accelerate your research and development. We leverage advanced CAR design principles, including affinity-tuned scFvs, optimized spacer and transmembrane domains, and tailored co-stimulatory profiles, to engineer CARs with superior specificity, reduced off-target toxicity, and enhanced persistence.

Customer Reviews

"We utilized Creative Biolabs for Viral Infection Specific CAR Construction targeting CMV. The IL-21 armored CAR-NK cells they engineered showed remarkably enhanced persistence and potent cytotoxic activity against virally infected cells in our in vivo models, outperforming our previous designs. The detailed metabolic pathway analysis they provided was invaluable." - Prof. Jn Sth

"Creative Biolabs' comprehensive workflow for CAR Construction saved us invaluable time and resources. Their expertise in vector selection and rigorous functional validation meant we received high-quality, ready-to-use CAR constructs and cells, accelerating our project timeline by several months. Their team was highly responsive and professional throughout the entire process." - Dr. An Wg

How to Contact Us

Ready to advance your next-generation CAR therapy project? Our expert team is eager to discuss your specific requirements and provide tailored solutions.

For more information or to discuss your specific project, please reach out to our team.

Products ordering information

Please note: We guarantee to offer you the best-in-class CARs products, which can undoubtedly satisfy various customers' needs. If you are unable to find the item of your choice, please don't hesitate to contact us at any time.

Reference

1. Canelo-Vilaseca, Marta et al. "Lymphodepletion chemotherapy in chimeric antigen receptor-engineered T (CAR-T) cell therapy in lymphoma." Bone marrow transplantation vol. 60,5 (2025): 559-567. https://doi.org/10.1038/s41409-025-02539-9. Distributed under Open Access License CC BY 4.0, without modification.