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CellRapeutics™ CD3+ T Cells from Celiac Disease Donor (XS-0426-XU213)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product consists of high-purity CD3+ T cells isolated from the peripheral blood of donors diagnosed with Celiac Disease. These cells represent a population primed by gluten-derived gliadin peptides and are isolated via immunomagnetic negative or positive selection to maintain their native physiological state. This cellular model is ideal for investigating the dysregulation of intestinal-homing T lymphocytes and the T-cell receptor repertoire involved in gluten-sensitive enteropathy.

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Donor Information

  • Product Name
  • CellRapeutics™ CD3+ T Cells from Celiac Disease Donor
  • Cat. No.
  • XS-0426-XU213
  • Donor Age
  • Young Adult
  • Donor Health
  • T cells are derived from donors with Celiac Disease. These cells exhibit specific sensitized profiles toward gluten-derived peptides and a predisposition for mucosal-homing in the gut environment.
  • Ethnicity
  • Diverse backgrounds available, predominantly Caucasian.
  • Anticoagulant
  • Acid Citrate Dextrose, optimized to stabilize T-cell metabolic homeostasis and prevent non-specific activation triggered by gluten-sensitive inflammatory mediators during processing.
  • Additional Donor Information
  • Each lot features CD3+ T cells from donors with confirmed Celiac disease. Profiles include HLA-DQ2/DQ8 status and gluten-free diet adherence to support studies on gluten-reactive T-cell responses.
  • Clinical Profile
  • History of gluten-free diet compliance, serological markers, and Marsh score for villous atrophy.

Additional Information

  • Medication History
  • Available upon request. Includes documentation regarding adherence to a Gluten-Free Diet and history of T-cell targeted immunomodulatory interventions.
  • Formulation
  • Cryopreserved in specialized freezing medium
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.
  • Storage
  • Store in liquid nitrogen vapor phase for long-term stability, maintain constant temperatures below -150°C to prevent loss of viability.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Perform rapid thawing in a 37°C water bath and dilute slowly with pre-warmed media to ensure optimal cell recovery and function.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 2.5E7 cells/vial, 5E7 cells/vial
  • Keywords
  • CellRapeutics™ CD3+ T Cells from Celiac Disease Donor, CD3+ T Cells, Celiac Disease

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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