×

CellRapeutics™ CD3+ T Cells from Systemic Lupus Erythematosus Donor (XS-0426-XU221)

Online Inquiry  Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product features CD3+ T cells harvested from donors with Systemic Lupus Erythematosus, characterized by profound defects in immune tolerance. These cells often exhibit aberrant signaling pathways, mitochondrial dysfunction, and skewed T-regulatory versus T-effector ratios. Purified through gentle immunomagnetic techniques, they serve as a robust model for investigating the molecular basis of multi-organ autoimmune flares and type I interferon-driven responses.

Specific Inquiry

  • Size:
  Add to Cart

Donor Information

  • Product Name
  • CellRapeutics™ CD3+ T Cells from Systemic Lupus Erythematosus Donor
  • Cat. No.
  • XS-0426-XU221
  • Donor Age
  • Young Adult
  • Donor Health
  • T cells exhibit profound dysregulation in peripheral tolerance, characterized by expanded effector populations and molecular signatures associated with systemic Type I interferon signaling and multi-organ autoimmune flares.
  • Ethnicity
  • Predominantly African American, Hispanic, and Asian backgrounds.
  • Anticoagulant
  • Heparin or Acid Citrate Dextrose, formulated to neutralize the interference of anti-phospholipid antibodies and DNA-containing immune complexes on T-cell surface integrity.
  • Additional Donor Information
  • Each lot features CD3+ T cells from SLE donors. Profiles include clinical flare status and medication history, ideal for studying T-cell signaling defects in lupus.
  • Clinical Profile
  • Documented flare frequency, ANA titer, and history of anti-dsDNA or anti-Smith antibodies.

Additional Information

  • Medication History
  • Available upon request. Includes history of corticosteroids, antimalarials, and immunosuppressants affecting T-cell subset distribution and signaling.
  • Formulation
  • Cryopreserved in specialized freezing medium
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.
  • Storage
  • Store in liquid nitrogen vapor phase for long-term stability, maintain constant temperatures below -150°C to prevent loss of viability.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Perform rapid thawing in a 37°C water bath and dilute slowly with pre-warmed media to ensure optimal cell recovery and function.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 2.5E7 cells/vial, 5E7 cells/vial
  • Keywords
  • CellRapeutics™ CD3+ T Cells from Systemic Lupus Erythematosus Donor, CD3+ T Cells, Systemic Lupus Erythematosus

Case Studies

Customer Reviews and Q&As

There are currently no customer reviews or questions for CellRapeutics™ CD3+ T Cells from Systemic Lupus Erythematosus Donor (XS-0426-XU221). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products

Online Inquiry

For any technical issues or product/service related questions, please leave your information below. Our team will contact you soon.

Key Updates
Newsletter. (Creative Biolabs Authorized) NEWSLETTER

The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders

LEARN MORE NEWSLETTER
New Solution. (Creative Biolabs Authorized) NEW SOLUTION

CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.

LEARN MORE SOLUTION
Novel Solution. (Creative Biolabs Authorized) NOVEL TECHNOLOGY

Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.

LEARN MORE NOVEL TECHNOLOGY
New Technology. (Creative Biolabs Authorized) NEW SOLUTION

Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.

LEARN MORE SOLUTION
Receive our latest news and insights.