CellRapeutics™ Leukopak from Multiple Sclerosis Donor (XS-0426-XU253)

Name: CellRapeutics™ Leukopak from Multiple Sclerosis Donor
SKU: XS-0426-XU253
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors with Multiple Sclerosis, this Leukopak captures the systemic immune dysregulation associated with central nervous system demyelination. The leucocyte population features an increased frequency of Th17 and Th1 cells, as well as B-cell subsets involved in the neuro-inflammatory cascade. It provides an expansive platform for studying the trafficking of lymphocytes across the blood-brain barrier and the evaluation of novel immunomodulatory strategies for autoimmune neurodegeneration.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Multiple Sclerosis Donor

Cat. No.
XS-0426-XU253

Donor Age
Young Adult

Donor Health
Donors exhibit neuro-inflammatory profiles. The leukocyte population is characterized by an increased frequency of Th1/Th17 effector cells with enhanced potential for central nervous system migration.

Ethnicity
Diverse backgrounds available, predominantly Caucasian.

Anticoagulant
Acid Citrate Dextrose, designed to maintain the integrity of the blood-brain barrier-crossing T cell subsets.

Additional Donor Information
Each lot features a Leukopak from donors with MS. Profiles include clinical phenotype and recent relapse history, supporting studies on the peripheral precursors of neuro-inflammatory T cells.

Clinical Profile
MS phenotype, time since last relapse, EDSS score, and history of disease-modifying therapies.

Additional Information

Medication History
Available upon request. Includes detailed records of Disease-Modifying Therapies, history of B-cell depletion, and use of corticosteroids for relapse management.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Multiple Sclerosis Donor, Leukopak, Multiple Sclerosis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.