CellRapeutics™ Leukopak from Hashimoto's Disease Donor (XS-0426-XU241)

Name: CellRapeutics™ Leukopak from Hashimoto's Disease Donor
SKU: XS-0426-XU241
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Collected from donors with Hashimoto's Thyroiditis, this product provides a concentrated pool of leukocytes involved in the chronic lymphocytic infiltration of the thyroid gland. The cell population features high titers of anti-TPO and anti-TG specific lymphocytes. It is optimized for studying Th1-mediated autoimmune destruction of thyroid follicles and the genetic markers associated with the most common cause of hypothyroidism.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Hashimoto's Disease Donor

Cat. No.
XS-0426-XU241

Donor Age
Middle-Aged

Donor Health
Donors exhibit chronic thyroiditis. The cell population is characterized by expanded autoreactive lymphocyte clones involved in thyroid tissue destruction and a systemic autoimmune-skewed repertoire.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, selected to stabilize thyroid-peroxidase reactive lymphocytes and maintain functional metabolic states.

Additional Donor Information
Each lot features a Leukopak from donors with chronic lymphocytic thyroiditis. Profiles include anti-TPO and anti-TG antibody status, facilitating research into the lymphocytic infiltration mechanisms of autoimmune hypothyroidism.

Clinical Profile
Documented TPO antibodies, history of hypothyroidism, and thyroid hormone replacement therapy status.

Additional Information

Medication History
Available upon request. Primarily documents long-term thyroid hormone replacement therapy and thyroid antibody status.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Hashimoto's Disease Donor, Leukopak, Hashimoto's Disease

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.