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CellRapeutics™ Leukopak from Myositis Donor (XS-0426-XU255)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Collected from donors with idiopathic inflammatory myopathies, this Leukopak captures the immune mediators of skeletal muscle destruction. The cellular profile often exhibits elevated levels of muscle-homing lymphocytes and specific interferon-regulated gene expression. It is an invaluable resource for researchers studying the pathogenesis of muscle fiber necrosis and the systemic autoimmune markers associated with extra-muscular manifestations.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Myositis Donor
  • Cat. No.
  • XS-0426-XU255
  • Donor Age
  • Middle-Aged
  • Donor Health
  • Donors exhibit idiopathic inflammatory myopathy. The cell population reflects a systemic autoimmune attack on muscle tissue, characterized by muscle-specific autoreactive lymphocyte populations and inflammatory myeloid activity.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Acid Citrate Dextrose or Heparin, formulated to stabilize muscle-infiltrating lymphocyte analogs and prevent enzyme-induced cell lysis.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with idiopathic inflammatory myopathies. Profiles include muscle enzyme levels and specific myositis-associated autoantibodies.
  • Clinical Profile
  • Specific subtype, myositis-specific autoantibody profile, muscle enzyme levels, and assessment of current muscle weakness or extra-muscular involvement.

Additional Information

  • Medication History
  • Available upon request. Records of high-dose corticosteroids, methotrexate, mycophenolate mofetil, and any history of biological therapy.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Myositis Donor, Leukopak, Myositis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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