CellRapeutics™ Leukopak from Sjogren's Syndrome Donor (XS-0426-XU264)

Name: CellRapeutics™ Leukopak from Sjogren's Syndrome Donor
SKU: XS-0426-XU264
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Procured from donors with Sjogren's Syndrome, this Leukopak offers a concentrated source of cells involved in autoimmune exocrinopathy. The cellular matrix is characterized by significant B-cell hyperreactivity and an increased frequency of circulating follicular T-helper cells. It is optimized for the study of the Type I Interferon signature and the molecular mechanisms underlying the lymphocytic infiltration of salivary and lacrimal glands.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Sjogren's Syndrome Donor

Cat. No.
XS-0426-XU264

Donor Age
Middle-Aged

Donor Health
Diagnosed with primary Sjögren's Syndrome. The leukocyte population is defined by profound B-cell hyperactivity, expanded plasmablast subsets, and T-cell signatures associated with exocrine gland infiltration.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, designed to preserve the viability of exocrine-gland-homing B and T lymphocytes.

Additional Donor Information
Each lot features a Leukopak from donors with primary Sjögren's syndrome. Profiles include anti-SSA/SSB status and objective sicca symptom measures, supporting research into exocrine-targeted lymphocytic responses.

Clinical Profile
Primary or secondary classification, anti-SSA/Ro and anti-SSB/La antibody status, and history of glandular or extra-glandular manifestations.

Additional Information

Medication History
Available upon request. Records of secretagogues, hydroxychloroquine, and systemic immunomodulatory agents for extraglandular manifestations.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Sjogren's Syndrome Donor, Leukopak, Sjogren's Syndrome

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.