CellRapeutics™ Leukopak from Type 1 Diabetes Donor (XS-0426-XU265)

Name: CellRapeutics™ Leukopak from Type 1 Diabetes Donor
SKU: XS-0426-XU265
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product features a comprehensive leucocyte collection from donors with Type 1 Diabetes Mellitus. The specimen is rich in memory T-cell populations primed against islet-cell antigens. It provides a robust primary cell source for investigating the failure of central and peripheral tolerance in the pancreatic microenvironment and for the identification of TCR repertoires associated with autoimmune beta-cell destruction.

Specific Inquiry

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Donor Information

Product Name
CellRapeutics™ Leukopak from Type 1 Diabetes Donor

Cat. No.
XS-0426-XU265

Donor Age
Young Adult

Donor Health
Diagnosed with T1DM. The cell population contains expanded autoreactive T-cell clones directed against pancreatic islet antigens, reflecting a state of organ-specific cellular autoimmune memory.

Ethnicity
Diverse backgrounds available, predominantly Caucasian.

Anticoagulant
Acid Citrate Dextrose, optimized to maintain the metabolic and functional integrity of insulin-autoreactive T cells.

Additional Donor Information
Each lot features a Leukopak from donors with autoimmune T1DM. Profiles include islet-specific autoantibody history and C-peptide levels, enabling the study of autoreactive T-cell populations in large volumes.

Clinical Profile
Age at onset, presence of T1D-associated autoantibodies, current HbA1c levels, and history of insulin pump or intensive insulin therapy.

Additional Information

Medication History
Available upon request. Primarily documents insulin replacement therapy regimens and any history of immunomodulatory interventions to preserve beta-cell function.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Type 1 Diabetes Donor, Leukopak, Type 1 Diabetes

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.