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CellRapeutics™ Leukopak from Type 2 Diabetes Donor (XS-0426-XU266)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Harvested from donors with Type 2 Diabetes (T2DM), this Leukopak captures the systemic immune environment of "metainflammation." The leucocyte population reflects the impact of chronic hyperglycemia and hyperinsulinemia, often exhibiting a polarized proinflammatory monocyte compartment and altered T-cell metabolic profiles. This product is prioritized for research into the intersection of immunometabolism and the systemic vascular complications associated with insulin resistance.

Specific Inquiry

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Type 2 Diabetes Donor
  • Cat. No.
  • XS-0426-XU266
  • Donor Age
  • Middle-Aged, Senior
  • Donor Health
  • Diagnosed with T2DM. Leukocytes exhibit signatures of metabolic exhaustion and chronic inflammatory priming, reflecting the systemic impact of insulin resistance and prolonged glycemic stress.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Heparin or Acid Citrate Dextrose, formulated to counteract the effects of hyperglycemia on cell membrane fragility and metabolic exhaustion.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with T2DM. Profiles include HbA1c levels, BMI, and metabolic syndrome markers, supporting research into chronic metabolic inflammation.
  • Clinical Profile
  • Disease duration, average HbA1c levels, Body Mass Index, and current management.

Additional Information

  • Medication History
  • Available upon request. Records of oral hypoglycemic agents, GLP-1 agonists, SGLT2 inhibitors, and management of metabolic comorbidities.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Type 2 Diabetes Donor, Leukopak, Type 2 Diabetes

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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