CellRapeutics™ Leukopak from Ulcerative Colitis Donor (XS-0426-XU267)

Name: CellRapeutics™ Leukopak from Ulcerative Colitis Donor
SKU: XS-0426-XU267
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Obtained from donors with biopsy-confirmed Ulcerative Colitis, this Leukopak provides a high-density pool of immune cells involved in mucosal-restricted gastrointestinal inflammation. The collection features an increased frequency of gut-homing T cells expressing integrin α4β7 and specific B-cell subsets associated with pANCA production. It is a vital tool for studying the systemic effects of barrier dysfunction and the discovery of novel therapeutic targets for colonic autoimmunity.

Specific Inquiry

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Donor Information

Product Name
CellRapeutics™ Leukopak from Ulcerative Colitis Donor

Cat. No.
XS-0426-XU267

Donor Age
Young Adult, Middle-Aged

Donor Health
Diagnosed with active or remitting Ulcerative Colitis. The leukocyte profile reflects colonic mucosal dysregulation, featuring expanded gut-homing lymphocyte subsets and altered innate immune sensing.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, optimized to preserve the integrin α4β7 expression and maintain the viability of colitogenic T cells.

Additional Donor Information
Each lot features a Leukopak from donors with confirmed UC. Profiles include disease extent and current inflammatory markers to support mucosal immunology research.

Clinical Profile
Disease extent, current Mayo Score or clinical remission status, and history of TNF-alpha inhibitors or other biologics.

Additional Information

Medication History
Available upon request. Includes history of 5-aminosalicylates, corticosteroids, and exposure to anti-TNF, anti-integrin, or JAK inhibitor therapies.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Ulcerative Colitis Donor, Leukopak, Ulcerative Colitis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.