CellRapeutics™ Leukopak from Vitiligo Donor (XS-0426-XU268)

Name: CellRapeutics™ Leukopak from Vitiligo Donor
SKU: XS-0426-XU268
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Derived from donors with active Vitiligo, this Leukopak captures the systemic leucocyte components of melanocyte-specific destruction. The cell population is characterized by the presence of circulating CD8⁺ T cells expressing cutaneous lymphocyte-associated antigen and a distinct Th1/IFN-γ cytokine profile. It serves as an essential resource for exploring the mechanisms of skin-specific autoimmunity and identifying peripheral markers of pigmentary loss progression.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Vitiligo Donor

Cat. No.
XS-0426-XU268

Donor Age
Young Adult

Donor Health
Clinically diagnosed with Vitiligo. Leukocytes exhibit a state of cutaneous-targeted autoimmunity, marked by the presence of melanocyte-specific cytotoxic T-cell clones and altered peripheral tolerance markers.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, prioritized to protect melanocyte-specific CD8⁺ T cells and maintain their cytotoxic potential.

Additional Donor Information
Each lot features a Leukopak from donors with active or stable vitiligo. Profiles include VASI scores and history of phototherapy, facilitating research into skin-homing CD8⁺ T-cell activity.

Clinical Profile
Type of vitiligo, estimated percentage of Body Surface Area affected, and disease stability.

Additional Information

Medication History
Available upon request. Documentation of topical corticosteroids/calcineurin inhibitors and systemic Janus Kinase inhibitors or phototherapy history.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Vitiligo Donor, Leukopak, Vitiligo

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.