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Lenti-MAGE-A3 TCR (6F9)-VP (VP-TCR-C243)

The ready-to-use lentiviral particles of Lenti-MAGE-A3 TCR (6F9)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of Human TCR will be driven by a CMV promotor. The target gene of TCR packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

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Specifications

  • Type of Therapeutics
  • T cell receptor
  • Target
  • MAGE-A3
  • Clone
  • 6F9
  • Promotor
  • CMV
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • Melanoma

Target

  • Introduction
  • This gene is a member of the MAGEA gene family. The members of this family encode proteins with
    50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show
    considerable variability, suggesting that the existence of this gene family enables the same function
    to be expressed under different transcriptional controls. The MAGEA genes are clustered at
    chromosomal location Xq28. They have been implicated in some hereditary disorders, such as
    dyskeratosis congenita.
    Alternative Names MAGEA3; Cancer/Testis
  • Alternative Names
  • CT1.4; MAGE4; MAGE4A; MAGE4B; MAGE-41; MAGE-X2; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Esophageal cancer; head and neck cancer; non-small cell pulmonary cancer; stomach cancer; Hodgkin's disease

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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