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Anti-UTY T cell receptor (YKII.39), pCDTCR1 (TCR-C256Z)

The vector of anti-UTY T cell receptor (TCR) is constructed for the engineering of T cell to target Human UTY. The T cells are genetically modified through transduction with a lentiviral vector expressing UTY-specific T cell receptor. And the vector product was designed for the treatment of Leukaemia.

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Details

  • Target
  • UTY
  • Target Species
  • Human
  • Epitope
  • MQQMRHKEV
  • Format
  • Non-modified
  • HLA
  • HLA-B*5201
  • Targeting Diseases
  • Leukaemia
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • YKII.39
  • Antibody Host
  • Mouse

Target

  • Official Symbol
  • UTY
  • Introduction
  • This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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