Anti-UTY T cell receptor (YKII.39), pCDTCR1(TCR-C256Z)

The vector of anti-UTY T cell receptor (TCR) is constructed for the engineering of T cell to target Human UTY. The T cells are genetically modified through transduction with a lentiviral vector expressing UTY-specific T cell receptor. And the vector product was designed for the treatment of Leukaemia.


Details


Target
UTY
Target Species
Human
Epitope
MQQMRHKEV
Format
Non-modified
HLA
HLA-B*5201
Targeting Diseases
Leukaemia
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
YKII.39
Antibody Host
Mouse

Target


Gene Name
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Official Symbol
UTY
Gene ID
Synonyms
UTY; UTY1; KDM6C; KDM6AL; ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Introduction
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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