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Novel Immune Checkpoints Discovery

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Cancer can evade immune detection by "closing" T cells through an inhibitory ligand-receptor interaction at an immune checkpoint. Destruction of these interacting antibodies or recombinant forms of receptors or ligands can stimulate very potent anti-tumor responses. Recent discoveries in this field have significantly expanded the range of treatments developed for patients, with the ultimate goal of giving long-term immunity to cancer. Therefore, identifying new immunotherapeutic targets provides important business value to our customers.

Novel Immune Checkpoints Discovery

Since many important immune checkpoint interactions have not been fully characterized, we continue to work extensively in this area. To do this, Creative Biolabs'unique and highly sensitive Surfarray™ cell microarray technology is optimized for the identification of novel immune checkpoints.

Key Features of Immune Checkpoints Discovery Services

Extremely High Success Rate

To date, Creative Biolabs has accumulated extensive phenotypic molecular screening experience through several projects, including projects on "difficult" molecules. We have screened for specific, repeatable molecules with a success rate of more than 50% due to the extensive collection of membrane proteins expressed by human cells.

High Specificity

Surfarray™'s low false positive rate ensures that months or years of research are not wasted to chase dead ends when verifying potential target hits. Immune Checkpoints Discovery using Surfarray™ cell microarray technology typically produces one or two repeatable hits that are specific to the test molecule and typically represent the primary receptor target and its different isoforms.

Creative Biolabs is dedicated to helping our worldwide customers shorten the discovery and development time in CAR-T cell therapy. We utilize unrivaled, proprietary drug design, study data, product candidate, advanced project life-cycle management, as well as real-time data to ensure the ideal outcomes.

For more detailed information, please feel free to contact us or directly send us an inquiry.

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