The vector of anti-CD30 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD30. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD30 antibody linked to b2c and CD3-zeta signaling domains. And the vector product was designed for the treatment of hodgkin lymphoma (HL) .
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ061||Anti-CD30 (HRS3) h(CD3ζ) CAR, pCDCAR1|
|CAR-LC060||Anti-CD30 (Brentuximab) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-MZ063||Anti-CD30 (HRS3) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC489||Lenti-CD30 CAR (scFv-CD28-CD3ζ, BerH2) Viral Particle|
|OAdCmodV-YX2149||Oncolytic Adenovirus (Capsid modified Ad5, phTERT-Δ55k, Anti-TNFRSF8), Viral particle|
|CAR-T-2-M301-4Z||Anti-CD30 scFv h(CD4-CD3ζ) CART, pCDCAR1|
|CAR-T-1-M301-G||Anti-CD30 scFv h(FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC491||Lenti-CD30 CAR (scFv-CD4-CD3ζ, BerH2) Viral Particle|
|CAR-T-2-M301-2Z||Anti-CD30 scFv h(CD28-CD3ζ) CART, pCDCAR1|
|OAdCmodV-YX2146||Oncolytic Adenovirus (Capsid modified Ad5, pCMV-Δ24/19k, Anti-TNFRSF8), Viral particle|
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