CD30

CD30 (Cluster of Differentiation 30), also known as TNFRSF8,is a is a trans-membrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is expressed by activated T and B cell, and is a receptor of TRAF2 and TRAF5, which madiate the signal transduction of NF-KB activation. CD30 is associated with anaplastic large T/B cell lymphoma. It is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors.CD30 and CD15 are also expressed on classical Hodgkin Lymphoma Reed-Sternberg cells.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC058 T cell Second HRS3 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC060 NK cell Second Brentuximab ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-MZ041 T cell First HRS3 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-MZ061 T cell First HRS3 ~8kb Retroviral scFv-CD3ζ Human Inquiry
CAR-MZ063 T cell Second HRS3 ~8kb Retroviral scFv-41BB-CD3ζ Human Inquiry
CAR-MZ064 T cell Second HRS3 ~8kb Retroviral scFv-OX40-CD3ζ Human Inquiry
CAR-T-1-M301-2 T cell First BerH2 8kb Lentiviral scFv-CD28 Human  Inquiry
CAR-T-1-M301-G T cell First BerH2 8kb Lentiviral scFv-FcεRIγ Human  Inquiry
CAR-T-1-M301-Z T cell First BerH2 8kb Lentiviral scFv-CD3ζ Human  Inquiry
CAR-T-2-M301-2G T cell Second BerH2 8kb Lentiviral scFv-CD28-FcεRIγ Human  Inquiry
CAR-T-2-M301-2Z T cell Second BerH2 8kb Lentiviral scFv-CD28-CD3ζ Human  Inquiry
CAR-T-2-M301-4G T cell Second BerH2 8kb Lentiviral scFv-CD4-FcεRIγ Human  Inquiry
CAR-T-2-M301-4Z T cell Second BerH2 8kb Lentiviral scFv-CD4-CD3ζ Human  Inquiry
CAR-T-2-M301-8Z T cell Second BerH2 8kb Lentiviral scFv-CD8-CD3ζ Human  Inquiry
CAR-T-2-M301-BZ T cell Second BerH2 8kb Lentiviral scFv-41BB-CD3ζ Human  Inquiry
CAR-T-2-M301-CZ T cell Second BerH2 8kb Lentiviral scFv-b2c-CD3ζ Human  Inquiry
CAR-T-3-M301-2BZ T cell Third BerH2 8kb Lentiviral scFv-CD28-41BB-CD3ζ Human  Inquiry
CAR-T-3-M301-2XZ T cell Third BerH2 8kb Lentiviral scFv-CD28-OX40-CD3ζ Human  Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC485 BerH2 Lentivirus First scFv (BerH2)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC486 BerH2 Lentivirus First scFv (BerH2)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC487 BerH2 Lentivirus First scFv (BerH2)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC488 BerH2 Lentivirus Second scFv (BerH2)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC489 BerH2 Lentivirus Second scFv (BerH2)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC490 BerH2 Lentivirus Second scFv (BerH2)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC491 BerH2 Lentivirus Second scFv (BerH2)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC492 BerH2 Lentivirus Second scFv (BerH2)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC493 BerH2 Lentivirus Second scFv (BerH2)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC494 BerH2 Lentivirus Second scFv (BerH2)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC495 BerH2 Lentivirus Third scFv (BerH2)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC496 BerH2 Lentivirus Third scFv (BerH2)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC548 HRS3 Lentivirus Second scFv (HRS3)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC762 HRS3 Lentivirus First scFv (HRS3)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC773 HRS3 Lentivirus First scFv (HRS3)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC774 HRS3 Lentivirus Second scFv (HRS3)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC775 HRS3 Lentivirus Second scFv (HRS3)-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
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