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C2

Complement C2 is a protein that in humans is encoded by the C2 gene. The protein encoded by this gene is part of the classical pathway of complement system, acting as a multi-domain serine protease. The complement system is a group of proteins that work together to destroy foreign invaders (such as bacteria and viruses), trigger inflammation, and remove debris from cells and tissues. When a foreign invader is detected, the complement pathway is turned on (activated) and the complement component 2 protein attaches (binds) to a similar protein called complement component 4. Together, these proteins form a complex called C3 convertase, which triggers further activation of the pathway, allowing the proteins of the complement system to participate in an immune response. Deficiency of C2 has been associated with certain autoimmune diseases.

Associated Disease
  • Autoimmune disease
  • Autoimmune arthritis
  • CAR Vector Products
  • CAR Viral Particles
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  • Receptor Construction:
CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M304-2 Anti-C2 scFv m(CD28) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M304-G Anti-C2 scFv m(FcεRIγ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M304-Z Anti-C2 scFv m(CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M304-2G Anti-C2 scFv m(CD28-FcεRIγ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M304-2Z Anti-C2 scFv m(CD28-CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M304-4G Anti-C2 scFv m(CD4-FcεRIγ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M304-4Z Anti-C2 scFv m(CD4-CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M304-8Z Anti-C2 scFv m(CD8-CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M304-BZ Anti-C2 scFv m(41BB-CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M304-CZ Anti-C2 scFv m(b2c-CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M304-2BZ Anti-C2 scFv m(CD28-41BB-CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M304-2XZ Anti-C2 scFv m(CD28-OX40-CD3ζ) CART, pCDCAR1 Mouse CIIC1; M2139 Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet

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