C2

Complement C2 is a protein that in humans is encoded by the C2 gene. The protein encoded by this gene is part of the classical pathway of complement system, acting as a multi-domain serine protease. The complement system is a group of proteins that work together to destroy foreign invaders (such as bacteria and viruses), trigger inflammation, and remove debris from cells and tissues. When a foreign invader is detected, the complement pathway is turned on (activated) and the complement component 2 protein attaches (binds) to a similar protein called complement component 4. Together, these proteins form a complex called C3 convertase, which triggers further activation of the pathway, allowing the proteins of the complement system to participate in an immune response. Deficiency of C2 has been associated with certain autoimmune diseases.

Associated Disease
  • Autoimmune disease
  • Autoimmune arthritis

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-T-1-M304-2 T cell First CIIC1; M2139 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-M304-G T cell First CIIC1; M2139 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-M304-Z T cell First CIIC1; M2139 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-2-M304-2G T cell Second CIIC1; M2139 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-M304-2Z T cell Second CIIC1; M2139 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-M304-4G T cell Second CIIC1; M2139 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-M304-4Z T cell Second CIIC1; M2139 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-M304-8Z T cell Second CIIC1; M2139 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-M304-BZ T cell Second CIIC1; M2139 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-M304-CZ T cell Second CIIC1; M2139 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-3-M304-2BZ T cell Third CIIC1; M2139 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-M304-2XZ T cell Third CIIC1; M2139 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC37 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC38 CIIC1; M2139 Lentivirus First scFv (CIIC1;M2139)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC39 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC40 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC41 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC42 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC43 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC44 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC45 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC46 CIIC1; M2139 Lentivirus Second scFv (CIIC1;M2139)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC47 CIIC1; M2139 Lentivirus Third scFv (CIIC1;M2139)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC48 CIIC1; M2139 Lentivirus Third scFv (CIIC1;M2139)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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