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DMTF1

DMTF1 is a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer.
  • CAR Vector Products
  • DMAb
CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type  
CAR-YC0012 Anti-DMTF1 (1A8) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 1A8 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0013 Anti-DMTF1 (1B7) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 1B7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0540 Anti-DMTF1 (11D62) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 11D62 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0541 Anti-DMTF1 (35K29) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 35K29 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0542 Anti-DMTF1 (5C6) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 5C6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0543 Anti-DMTF1 (8C92) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 8C92 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0912 Anti-DMTF1 (1A8) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 1A8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0913 Anti-DMTF1 (1B7) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 1B7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC1440 Anti-DMTF1 (11D62) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 11D62 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC1441 Anti-DMTF1 (35K29) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 35K29 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC1442 Anti-DMTF1 (5C6) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 5C6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC1443 Anti-DMTF1 (8C92) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 8C92 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC1444 Anti-DMTF1 (DMTF5I250) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human DMTF5I250 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YC0544 Anti-DMTF1 (DMTF5I250) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human DMTF5I250 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet

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