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FGFR2

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The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP7250 Anti-FGFR2 (XHM426) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM426 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7251 Anti-FGFR2 (XHM426) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM426 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7252 Anti-FGFR2 (XHM427) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM427 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7253 Anti-FGFR2 (XHM427) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM427 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7254 Anti-FGFR2 (XHM428) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM428 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7255 Anti-FGFR2 (XHM428) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM428 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7256 Anti-FGFR2 (XHM429) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM429 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7257 Anti-FGFR2 (XHM429) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM429 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7258 Anti-FGFR2 (FR2-14_H1/L1) h(CD28-CD3ζ) CAR, pCDCAR1 Human FR2-14_H1/L1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7259 Anti-FGFR2 (FR2-14_H1/L1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human FR2-14_H1/L1 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7260 Anti-FGFR2 (XHM430) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM430 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7261 Anti-FGFR2 (XHM430) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM430 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7262 Anti-FGFR2 (EML2262) h(CD28-CD3ζ) CAR, pCDCAR1 Human EML2262 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7263 Anti-FGFR2 (EML2262) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human EML2262 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7264 Anti-FGFR2 (6L19) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6L19 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7265 Anti-FGFR2 (6L19) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 6L19 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7266 Anti-FGFR2 (XHM431) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM431 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7303 Anti-FGFR2 (BA0282) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human BA0282 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7304 Anti-FGFR2 (XHM435) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM435 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7305 Anti-FGFR2 (XHM435) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM435 Rat scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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