FRα (Folate receptor-alpha)

Folate receptor-alpha (FRα), also known as FOLR1, FBP, FOLR, FR1, is a glycosylphosphatidyl-inositol-linked protein encoded by FOLR1 gene. This receptor is a membrane-bound protein with high affinity for binding and transporting physiologic levels of folate into cells. Compare to normal cells, FRα is overexpressed on ovarian and several other epithelial malignancies including renal cancer, lung cancer and breast cancer. Therefore, FRα can be used as a target for imaging and therapy.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC006 T cell Second C4 ~8kb Lentiviral scFv-CD27-CD3ζ Human Inquiry
CAR-LC040 T cell Second MOv19 ~8kb Lentiviral scFv-ICOS-CD3ζ Mouse Inquiry
CAR-LC164 T cell Second C4 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC165 T cell First C4 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-LC360 T cell Second MOv19 ~8kb Lentiviral scFv(MSLN)-CD3ζ/scFv(FRA)-CD28 Mouse Inquiry
CAR-MZ154 T cell First MOv19 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ155 T cell Second MOv19 ~8kb Lentiviral scFv-CD137-CD3ζ Mouse Inquiry
CAR-T-1-M313-2 T cell First MOv19 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-M313-G T cell First MOv19 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-M313-Z T cell First MOv19 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-2-M313-2G T cell Second MOv19 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-M313-2Z T cell Second MOv19 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-M313-4G T cell Second MOv19 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-M313-4Z T cell Second MOv19 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-M313-8Z T cell Second MOv19 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-M313-BZ T cell Second MOv19 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-M313-CZ T cell Second MOv19 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-3-M313-2BZ T cell Third MOv19 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-M313-2XZ T cell Third MOv19 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC512 C4 Lentivirus Second scFv (C4)-CD27-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC532 MOv19 Lentivirus Second scFv (MOv19)-ICOS-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC648 C4 Lentivirus Second scFv (C4)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC649 C4 Lentivirus First scFv (C4)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC849 MOv19 Lentivirus First scFv (MOv19)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC850 MOv19 Lentivirus Second scFv (MOv19)-CD137-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-048-3343

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