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FZD6

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This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ1371 Anti-FZD6 (CBXF-2693) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBXF-2693 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1372 Anti-FZD6 (CBXF-1241) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1241 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1373 Anti-FZD6 (CBXF-2189) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBXF-2189 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1374 Anti-FZD6 (CBXF-2088) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Monkey CBXF-2088 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1375 Anti-FZD6 (CBXF-0992) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBXF-0992 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1376 Anti-FZD6 (CBXF-2470) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBXF-2470 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1377 Anti-FZD6 (CBXF-3269) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBXF-3269 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1378 Anti-FZD6 (CBXF-1695) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBXF-1695 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4795 Anti-FZD6 (CBXF-2693) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBXF-2693 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4796 Anti-FZD6 (CBXF-1241) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1241 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4797 Anti-FZD6 (CBXF-2189) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBXF-2189 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4798 Anti-FZD6 (CBXF-2088) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Monkey CBXF-2088 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4799 Anti-FZD6 (CBXF-0992) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBXF-0992 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4800 Anti-FZD6 (CBXF-2470) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBXF-2470 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4801 Anti-FZD6 (CBXF-3269) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBXF-3269 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4802 Anti-FZD6 (CBXF-1695) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBXF-1695 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-0320ZP1045 Anti-FZD6 (DS1372AB) h(CD28-CD3ζ) CAR, pCDCAR1 Human DS1372AB Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1046 Anti-FZD6 (DS1372AB) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human DS1372AB Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1047 Anti-FZD6 (D16E5) h(CD28-CD3ζ) CAR, pCDCAR1 Human D16E5 Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1048 Anti-FZD6 (D16E5) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D16E5 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
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