PTPN11

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ1789 Anti-PTPN11 (CBXS-4890) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Dog CBXS-4890 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1790 Anti-PTPN11 (CBXS-5174) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXS-5174 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1791 Anti-PTPN11 (CBXS-5216) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5216 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1792 Anti-PTPN11 (CBXS-5577) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-5577 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1793 Anti-PTPN11 (CBXS-5578) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5578 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1794 Anti-PTPN11 (CBXS-1210) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Human CBXS-1210 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1795 Anti-PTPN11 (CBXS-1211) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-1211 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1796 Anti-PTPN11 (CBXS-1738) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXS-1738 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1797 Anti-PTPN11 (M163) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Human M163 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5213 Anti-PTPN11 (CBXS-4890) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Dog CBXS-4890 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5214 Anti-PTPN11 (CBXS-5174) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXS-5174 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5215 Anti-PTPN11 (CBXS-5216) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-5216 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5216 Anti-PTPN11 (CBXS-5577) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-5577 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5217 Anti-PTPN11 (CBXS-5578) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-5578 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5218 Anti-PTPN11 (CBXS-1210) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Human CBXS-1210 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5219 Anti-PTPN11 (CBXS-1211) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-1211 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5220 Anti-PTPN11 (CBXS-1738) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXS-1738 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5221 Anti-PTPN11 (M163) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Human M163 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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