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SEMA4G

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
  • CAR Vector Products

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    CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
    XS-1222-ZP188 SEMA4G (PLXNB2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human SEMA4G-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
    XS-1222-ZP1588 SEMA4G (PLXNB2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human SEMA4G-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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