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SORD

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Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ2775 Anti-SORD (CBXS-3626) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3626 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2776 Anti-SORD (CBXS-5976) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5976 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2777 Anti-SORD (CBXS-3686) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3686 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2778 Anti-SORD (CBXS-3711) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3711 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2779 Anti-SORD (CBXS-3762) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3762 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2780 Anti-SORD (CBXS-3998) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3998 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2781 Anti-SORD (CBXS-4329) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-4329 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2782 Anti-SORD (CBXS-5017) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5017 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2783 Anti-SORD (15H2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 15H2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2784 Anti-SORD (9E7) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9E7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2785 Anti-SORD (CBXS-6103) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-6103 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2786 Anti-SORD (CBXS-0651) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0651 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2787 Anti-SORD (CBXS-0653) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-0653 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2788 Anti-SORD (CBXS-0654) h(41BB-CD3ζ) CAR, pCDCAR1 Rat CBXS-0654 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2789 Anti-SORD (CBXS-1409) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-1409 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2790 Anti-SORD (CBXS-2609) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2609 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2791 Anti-SORD (CBXS-2715) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2715 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ2792 Anti-SORD (CBXS-2850) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2850 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ6199 Anti-SORD (CBXS-3626) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-3626 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ6200 Anti-SORD (CBXS-5976) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-5976 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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