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TGFB1

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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP6107 Anti-TGFB1 (XHM489) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM489 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6108 Anti-TGFB1 (XHM489) h(41BB-CD3ζ) CAR, pCDCAR1 Human XHM489 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6109 Anti-TGFB1 (XHM490) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM490 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6110 Anti-TGFB1 (XHM490) h(41BB-CD3ζ) CAR, pCDCAR1 Human XHM490 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6111 Anti-TGFB1 (1D11.16.8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1D11.16.8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6112 Anti-TGFB1 (1D11.16.8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1D11.16.8 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6113 Anti-TGFB1 (12H5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 12H5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6114 Anti-TGFB1 (12H5) h(41BB-CD3ζ) CAR, pCDCAR1 Human 12H5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6115 Anti-TGFB1 (XHM491) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM491 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6116 Anti-TGFB1 (XHM491) h(41BB-CD3ζ) CAR, pCDCAR1 Human XHM491 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6117 Anti-TGFB1 (XHM492) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM492 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6118 Anti-TGFB1 (XHM492) h(41BB-CD3ζ) CAR, pCDCAR1 Human XHM492 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6119 Anti-TGFB1 (XHM493) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM493 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6120 Anti-TGFB1 (XHM493) h(41BB-CD3ζ) CAR, pCDCAR1 Human XHM493 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6121 Anti-TGFB1 (4E13) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4E13 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6122 Anti-TGFB1 (4E13) h(41BB-CD3ζ) CAR, pCDCAR1 Human 4E13 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6123 Anti-TGFB1 (2Ar2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2Ar2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6124 Anti-TGFB1 (2Ar2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2Ar2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6125 Anti-TGFB1 (7F6) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7F6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6126 Anti-TGFB1 (7F6) h(41BB-CD3ζ) CAR, pCDCAR1 Human 7F6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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