All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
VivoCAR™ Anti-CD117 (NEG024) h(CD28-41BB-CD3z) CAR circRNA utilizes the NEG024 clone to target the SCF receptor on aggressive myeloid leukemia and gastrointestinal stromal tumors (GIST). In the context of in vivo therapy, this clone is critical for its ability to block oncogenic c-Kit signaling while simultaneously triggering CAR-T cytolysis. The circRNA platform ensures a transient and high-potency response, allowing for a strategic depletion of CD117+ malignant cells. This non-integrating approach is essential for protecting the host's long-term hematopoietic reservoir through its programmable, transient nature.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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