Esbp Pep-LNP

Cat. No.: TDLD-0825-LD107

Esbp Pep-LNP

Esbp Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the Esbp peptide, this LNP exhibits high affinity for E-selectin, which is highly expressed on the surface of endothelial cells at sites of inflammation, metastatic tumors, and leukemia, enabling active targeted delivery. Our LNP is prepared using DSPE-PEG-Esbp and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of Esbp Pep-LNP include developing targeted therapeutics and imaging agents for inflammatory diseases, metastatic cancers, and hematological malignancies, studying E-selectin biology and its role in disease progression, and evaluating novel strategies for enhancing tissue penetration and cellular uptake efficiency at specific pathological sites. Please note that this product is intended for research purposes only.