Creative Biolabs

Esbp Pep-LNP

Cat. No.: TDLD-0825-LD107

Esbp Pep-LNP

Esbp Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the Esbp peptide, this LNP exhibits high affinity for E-selectin, which is highly expressed on the surface of endothelial cells at sites of inflammation, metastatic tumors, and leukemia, enabling active targeted delivery. Our LNP is prepared using Targeting Module and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of Esbp Pep-LNP include developing targeted therapeutics and imaging agents for inflammatory diseases, metastatic cancers, and hematological malignancies, studying E-selectin biology and its role in disease progression, and evaluating novel strategies for enhancing tissue penetration and cellular uptake efficiency at specific pathological sites. Please note that this product is intended for research purposes only.

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SPECIFIC INQUIRY
Payload:
Modification:
Lipid Formulation:
Dye:
Concentration:
Quantity:
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For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA; Others
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine; Other
Module Type Peptide
Targeting Module Esbp Peptide
Target Tumor cells
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102; Other
Dye Unlabeled; DiR; DiD; DiO; DiI; Other
Application Targeted Delivery; Gene Therapy
Format Liquid
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Shipping Dry Ice
Storage Store at -80°C
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