RVG29 Pep-LNP

Cat. No.: TDLD-0825-LD72

RVG29 Pep-LNP

RVG29 Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient brain-targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the RVG29 peptide, this LNP demonstrates exceptional targeting capabilities by selectively binding to nicotinic acetylcholine receptors (nAChRs) on neural cells, enabling it to traverse the blood-brain barrier (BBB) with high efficacy. Our LNP is prepared using DSPE-PEG-RVG29 and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of RVG29 Pep-LNP span a wide range of neuroscience research, including gene therapy for neurodegenerative diseases like Alzheimer's and Parkinson's, mRNA-based therapies for CNS disorders, and gene editing in brain cells. Please note that this product is intended for research purposes only.