K237 Pep-LNP

Cat. No.: TDLD-0825-LD106

K237 Pep-LNP

K237 Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the K237 peptide, this LNP specifically binds to the KDR receptor on the surface of tumor neovasculature and tumor cells, thereby blocking the biological effects induced by VEGF binding to KDR. Our LNP is prepared using DSPE-PEG-K237 and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of K237 Pep-LNP include developing targeted anti-angiogenic and anti-tumor therapeutics, creating receptor-specific imaging probes for tumor vasculature, studying KDR receptor biology and its role in tumor growth, and evaluating novel strategies for selectively delivering payloads to tumor cells and their supporting vasculature. Please note that this product is intended for research purposes only.