ActivatorPep™ AdV Select (CA-LX119)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Product Name
ActivatorPep™ AdV Select

Cat. No.
CA-LX119

Product Summary
Creative Biolabs provides an extensive cell activation reagents including Expansion Kits and Activator peptides for global custom, which are suitable to many applications, such as in vitro stimulation antigen-specific cells. AdV Select - research grade is a peptide pool of 50 lyophilized oligopeptides, consisting of MHC class I and class II restricted peptides derived from different proteins of human adenovirus (AdV), serotypes 2 and 5. Which can be used for in vitro stimulation of AdV Select-specific CD4+ and CD8+ T cells.

Background Information
Adenoviruses (AdV) are non-enveloped, ubiquitous, lytic double‑stranded DNA viruses. Up to now, 52 different human serotypes (1-52), divided into six species (A-F), are described. AdV infections are associated with significant morbidity and mortality after hematopoetic stem cell transplantations.

Applications
Stimulation Reagents

Cross-reactivity
No significant cross-reactivity was observed among analytes in this panel.

Species Reactivity
Human

Purity or Quality Grade
Research Grade

Downstream Application
Pulsing of antigen-presenting cells for research;
Detection and analysis of antigen-specific CD4+ and CD8+ effector/memory T cells in PBMCs;

Product Size
for stimulation of 1×108 cells

Shipping Condition
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage Conditions
Store at -20°C.

Shelf life
> 6 Months from date of receipt under proper storage condition.

Product Use Statement
For research use only, not for diagnostic or therapeutic use.

Product Features
Efficient expansion and increased survival rate of Ag-specific T cells;
Provides a gentle activation stimulus that maintains high viability of activated and expanded T cells;

Principle of the Assay
Peptide Pools have been specially developed for efficient in vitro stimulation of antigen-specific CD4+ and CD8+ T cells. Stimulation of T cells with Peptide Pools causes the secretion of effector cytokines and upregulation of activation markers, which then allows the detection or isolation of antigen-specific T cells.

Research Category
Immunology

Panel Type
Stimulation for CD4+ and CD8+ T cells

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

ActivatorPep™ AdV Select (CA-LX119)

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