ActivatorPep™ HHV1 Envelope Glycoprotein D (CA-LX111)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Product Name
ActivatorPep™ HHV1 Envelope Glycoprotein D

Cat. No.
CA-LX111

Product Summary
Creative Biolabs provides an extensive cell activation reagents including Expansion Kits and Activator peptides for global custom, which are suitable to many applications, such as in vitro stimulation antigen-specific cells. HHV1 is a peptice pool that consists mainly of 15-mer sequences with 11 amino acids (aa) overlap, covering the complete sequence of the human herpes simplex virus 1 (HHV1) envelope glycoprotein D (UniProtKB Acc. no. P57083). Which can be used for in vitro stimulation of HHV1 Envelope Glycoprotein D-specific T cells.

Background Information
HHV-1, also known as HSV-1, belongs to the family of Herpesviridae which are widespread among humans. Once infected, the virus persists for life. The Herpesviridae are not only known to cause various diseases like Herpes labialis or Herpes genitalis, but also life threatening complications in immunocompromized individuals (e.g. HHV-induced encephalitis).

Applications
Stimulation Reagents

Cross-reactivity
No significant cross-reactivity was observed among analytes in this panel.

Species Reactivity
Human

Purity or Quality Grade
Research Grade

Downstream Application
Pulsing of antigen-presenting cells for research;
Detection and analysis of antigen-specific CD4+ and CD8+ effector/memory T cells in PBMCs;

Product Size
for stimulation of 1×108 cells

Shipping Condition
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage Conditions
Store at -20°C.

Shelf life
> 6 Months from date of receipt under proper storage condition.

Product Use Statement
For research use only, not for diagnostic or therapeutic use.

Product Features
Efficient expansion and increased survival rate of Ag-specific T cells;
Provides a gentle activation stimulus that maintains high viability of activated and expanded T cells;

Principle of the Assay
HHV1 Envelope Glycoprotein D Peptide Pools have been specially developed for efficient in vitro stimulation of antigen-specific CD4+ and CD8+ T cells, as peptides of 15 amino acid length with 11 amino acid overlap represent the optimized solution for stimulating both CD4+ and CD8+ T cells in various applications. Stimulation of T cells with Peptide Pools causes the secretion of effector cytokines and upregulation of activation markers, which then allows the detection or isolation of antigen-specific T cells.

Research Category
Immunology

Panel Type
Stimulation for CD4+ and CD8+ T cells

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

ActivatorPep™ HHV1 Envelope Glycoprotein D (CA-LX111)

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