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Anti-HBZ T cell receptor, pCDTCR1 (TCR-ZP506)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-HBZ T cell receptor (TCR) is constructed for the engineering of T cell to target Human. The T cells are genetically modified through transduction with a lentiviral vector expressing HBZ-specific T cell receptor. And the vector product was designed for the treatment of Colorectal cancer.

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Details

  • Target
  • HBZ
  • Target Species
  • Human
  • Epitope
  • KLSELHAYI
  • Format
  • Non-modified
  • Allele
  • HLA-DRB5
  • Targeting Cell Type
  • T cell
  • Targeting Diseases
  • Colorectal cancer
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • KE8
  • Host Species
  • Human

Target

  • Introduction
  • Zeta globin is an alpha like hemoglobin. The zeta globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha globin is produced throughout fetal and adult life. The zeta globin gene is a member of the human alpha globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' zeta pseudozeta mu pseudoalpha 1 alpha 2 alpha 1 theta1 3'.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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