CellRapeutics™ Leukopak from Hyperthyroidism Donor (XS-0426-XU270)

Name: CellRapeutics™ Leukopak from Hyperthyroidism Donor
SKU: XS-0426-XU270
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Collected from donors presenting with hyperthyroidism, this Leukopak reflects the immune system's state under the influence of excessive thyroid hormone levels. The matrix contains circulating thyroid-stimulating immunoglobulin producing B cells and T cells that exhibit altered metabolic and proliferative kinetics. It provides a specialized model for studying the endocrine-immune crosstalk and the systemic effects of thyrotoxicosis on lymphoid homeostasis.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Hyperthyroidism Donor

Cat. No.
XS-0426-XU270

Donor Age
Young Adult, Middle-Aged

Donor Health
Clinically diagnosed with Hyperthyroidism. Leukocytes reflect a systemic hypermetabolic environment, showing altered cellular respiration markers and shifts in baseline cytokine secretion associated with elevated thyroid hormones.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, focused on mitigating high metabolic-rate-induced cellular stress during the apheresis procedure.

Additional Donor Information
Each lot features a Leukopak from donors with non-autoimmune or unspecified hyperthyroidism. Profiles include thyroid hormone levels and clinical symptoms, focusing on the systemic effects of thyrotoxicosis on the immune system.

Clinical Profile
Underlying etiology, thyroid function test history, TSH receptor antibody status, and history of antithyroid medications or RAI treatment.

Additional Information

Medication History
Available upon request. Documentation of antithyroid medications, beta-blockers, and history of radioactive iodine treatment.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Hyperthyroidism Donor, Leukopak, Hyperthyroidism

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.