CellRapeutics™ Leukopak from Scleroderma Donor (XS-0426-XU262)

Name: CellRapeutics™ Leukopak from Scleroderma Donor
SKU: XS-0426-XU262
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors diagnosed with Systemic Sclerosis, this Leukopak captures the complex leucocyte environment associated with systemic fibrosis and vasculopathy. The cell population is notably enriched with profibrotic myeloid subsets and T-helper cells secreting Type 2 cytokines that drive fibroblast activation. This product serves as a critical resource for investigating the immunological triggers of excessive collagen deposition and identifying biomarkers for interstitial lung disease secondary to Scleroderma.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Scleroderma Donor

Cat. No.
XS-0426-XU262

Donor Age
Middle-Aged

Donor Health
Diagnosed with Systemic Sclerosis. The immune profile is characterized by a pro-fibrotic leukocyte bias, with altered T-cell subsets and monocytes that orchestrate fibroblast activation and vascular endothelial stress.

Ethnicity
Diverse backgrounds available, predominantly African American and Hispanic cohorts.

Anticoagulant
Acid Citrate Dextrose, formulated to preserve the fibrotic-related monocyte subsets and stabilize delicate vascular-homing cells.

Additional Donor Information
Each lot features a Leukopak from donors with systemic sclerosis. Profiles specify limited or diffuse cutaneous involvement and presence of pulmonary fibrosis, facilitating research into T-cell driven fibrotic signaling.

Clinical Profile
Classification, specific autoantibody profile, and documentation of systemic involvement.

Additional Information

Medication History
Available upon request. Documentation of immunosuppressive therapy, vasodilators, and treatments for fibrotic organ involvement.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Scleroderma Donor, Leukopak, Scleroderma

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.