CellRapeutics™ Leukopak from Secondary Progressive Multiple Sclerosis Donor (XS-0426-XU292)

Name: CellRapeutics™ Leukopak from Secondary Progressive Multiple Sclerosis Donor
SKU: XS-0426-XU292
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors who have transitioned to the Secondary Progressive phase of Multiple Sclerosis, this Leukopak reflects a shift toward chronic, compartmentalized neuro-inflammation and progressive neurodegeneration. The cell population is characterized by markers of persistent immune exhaustion and skewed myeloid-to-lymphoid ratios. This product is a critical resource for researchers analyzing the systemic drivers of cumulative axonal loss and identifying biomarkers that differentiate progressive phenotypes from early-stage relapsing disease.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Secondary Progressive Multiple Sclerosis Donor

Cat. No.
XS-0426-XU292

Donor Age
Middle-Aged, Senior

Donor Health
Diagnosed with SPMS. The immune repertoire reflects a transition toward chronic, sustained neuro-inflammation and accelerated immune senescence, featuring a more prominent accumulation of exhausted T-cell subsets and pro-inflammatory myeloid precursors.

Ethnicity
Diverse backgrounds available, predominantly Caucasian.

Anticoagulant
Acid Citrate Dextrose, optimized to preserve the chronically activated/exhausted T cell phenotypes for specialized research.

Additional Donor Information
Each lot features a Leukopak from donors with SPMS. Profiles emphasize EDSS scores and disease duration, providing cells for research into progressive neurodegeneration and chronic immune activation.

Clinical Profile
Transition history from RRMS, rate of disability progression, current EDSS score, and history of specialized SPMS treatments.

Additional Information

Medication History
Available upon request. Records of specialized DMTs for progressive forms, history of prior relapsing-stage treatments, and symptomatic neurological medications.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Secondary Progressive Multiple Sclerosis Donor, Leukopak, Secondary Progressive Multiple Sclerosis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.