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CellRapeutics™ Serum from Pemphigus Donor (XS-0426-XU160)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors with Pemphigus Vulgaris or Foliaceus, this serum is characterized by high titers of autoantibodies against desmogleins. It serves as a specialized tool for investigating the loss of intraepidermal adhesion and the B-cell-mediated pathways that drive the destruction of desmosomal proteins.

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Donor Information

  • Product Name
  • CellRapeutics™ Serum from Pemphigus Donor
  • Cat. No.
  • XS-0426-XU160
  • Donor Age
  • Middle-Aged
  • Donor Health
  • Diagnosed with Pemphigus. Serum is distinguished by autoantibodies targeting desmogleins, leading to systemic signatures of intraepidermal acantholysis.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • None (separated via centrifugation following natural coagulation).
  • Additional Donor Information
  • Each lot features serum from donors with Pemphigus Vulgaris or Foliaceus. Profiles include anti-Desmoglein 1 and 3 antibody titers, mucosal/cutaneous involvement history, and history of Rituximab therapy.
  • Clinical Profile
  • Subtype, anti-Desmoglein 1/3 antibody titers, and clinical severity.

Additional Information

  • Medication History
  • Available upon request. Documentation of high-dose systemic Corticosteroids, Rituximab, and adjuvant immunosuppressive therapy to maintain remission.
  • Formulation
  • Frozen
  • Cell Viability
  • Cell-free (no residual erythrocytes or leukocytes).
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each serum batch undergoes rigorous IRB-compliant screening, ensuring pathogen-free safety, consistent physicochemical properties, and standardized clinical characterization of disease-specific biomarkers to provide a reliable, high-purity biological matrix.
  • Storage
  • Store at -80°C or below for long-term stability, or at -20°C for up to 6 months, avoid repeated freeze-thaw cycles to preserve product quality.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Thaw slowly on ice or at 4°C and centrifuge to remove cryoprecipitates, immediate aliquoting upon first thaw is recommended to maintain autoantibody functional integrity.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 1ML
  • Keywords
  • CellRapeutics™ Serum from Pemphigus Donor, Serum, Pemphigus

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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