CellRapeutics™ Leukopak from Hypercholesterolemia Donor (XS-0426-XU246)

Name: CellRapeutics™ Leukopak from Hypercholesterolemia Donor
SKU: XS-0426-XU246
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak is harvested from donors with clinically diagnosed Hypercholesterolemia, capturing the leukocyte profile associated with chronic lipid metabolic stress. The cellular composition reflects the systemic impact of elevated low-density lipoprotein levels, often exhibiting a pro-inflammatory skewing of the monocyte compartment and altered scavenger receptor expression. This product is a primary resource for investigating the role of innate immunity in atherogenesis and the metabolic programming of circulating macrophages.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Hypercholesterolemia Donor

Cat. No.
XS-0426-XU246

Donor Age
Middle-Aged, Senior

Donor Health
Donors exhibit a chronic metabolic and pro-atherogenic environment. Leukocytes reflect lipid-induced inflammatory priming, particularly within the circulating monocyte and macrophage precursor populations.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Heparin, optimized to prevent lipid-induced cell clumping and preserve the surface receptor integrity of monocytes.

Additional Donor Information
Each lot features a Leukopak from donors with elevated LDL cholesterol. Profiles include lipid panels and statin use, facilitating research into the effects of hyperlipidemia on monocyte activation and atherosclerosis.

Clinical Profile
Lipid profile history, presence of cardiovascular comorbidities, and history of statin or other lipid-lowering therapies.

Additional Information

Medication History
Available upon request. Documentation of statins, ezetimibe, or PCSK9 inhibitors and management of associated metabolic conditions.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Hypercholesterolemia Donor, Leukopak, Hypercholesterolemia

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.