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CellRapeutics™ Serum from Seronegative Myasthenia Gravis Donor (XS-0426-XU188)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This unique serum is sourced from Myasthenia Gravis patients who lack detectable antibodies against the acetylcholine receptor. The samples are essential for the study of "low-affinity" antibodies or alternative targets. This product provides a rare and specialized matrix for improving diagnostic sensitivity and understanding the divergent pathogenic mechanisms of neuromuscular junction failure.

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Donor Information

  • Product Name
  • CellRapeutics™ Serum from Seronegative Myasthenia Gravis Donor
  • Cat. No.
  • XS-0426-XU188
  • Donor Age
  • Young Adult, Middle-Aged
  • Donor Health
  • Clinically diagnosed with MG but testing negative for standard AChR and MuSK antibodies. Serum is characterized by alternative pathogenic factors or low-affinity antibodies targeting the neuromuscular junction.
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • None (separated via centrifugation following natural coagulation).
  • Additional Donor Information
  • Each lot features serum from donors with clinically diagnosed MG who lack AChR and MuSK antibodies. This is critical for investigating alternative pathogenic mechanisms and novel autoantibodies.
  • Clinical Profile
  • Myasthenia Gravis Foundation of America classification, absence of AChR/MuSK antibodies, and treatment history.

Additional Information

  • Medication History
  • Available upon request. Records of Pyridostigmine, corticosteroids, and aggressive immunosuppressive or biological regimens to manage generalized symptoms.
  • Formulation
  • Frozen
  • Cell Viability
  • Cell-free (no residual erythrocytes or leukocytes).
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each serum batch undergoes rigorous IRB-compliant screening, ensuring pathogen-free safety, consistent physicochemical properties, and standardized clinical characterization of disease-specific biomarkers to provide a reliable, high-purity biological matrix.
  • Storage
  • Store at -80°C or below for long-term stability, or at -20°C for up to 6 months, avoid repeated freeze-thaw cycles to preserve product quality.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Thaw slowly on ice or at 4°C and centrifuge to remove cryoprecipitates, immediate aliquoting upon first thaw is recommended to maintain autoantibody functional integrity.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 1ML
  • Keywords
  • CellRapeutics™ Serum from Seronegative Myasthenia Gravis Donor, Serum, Seronegative Myasthenia Gravis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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