The vector of anti-CD47 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD47. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD47 antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of B-cell malignancies.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-1-L344-2||Anti-CD47 scFv h(CD28) CART, pCDCAR1|
|CAR-T-2-L344-CZ||Anti-CD47 scFv h(b2c-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC132||Lenti-CD47 CAR (scFv-CD28-OX40-CD3ζ, B6H12.2) Viral Particle|
|VP-CAR-LC128||Lenti-CD47 CAR (scFv-CD8-CD3ζ, B6H12.2) Viral Particle|
|VP-CAR-LC127||Lenti-CD47 CAR (scFv-CD4-CD3ζ, B6H12.2) Viral Particle|
|VP-CAR-LC131||Lenti-CD47 CAR (scFv-CD28-41BB-CD3ζ, B6H12.2) Viral Particle|
|CAR-T-2-L344-2G||Anti-CD47 scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC126||Lenti-CD47 CAR (scFv-CD4-FcεRIγ, B6H12.2) Viral Particle|
|VP-CAR-LC122||Lenti-CD47 CAR (scFv-FcεRIγ, B6H12.2) Viral Particle|
|VP-CAR-LC125||Lenti-CD47 CAR (scFv-CD28-CD3ζ, B6H12.2) Viral Particle|
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